Hypotensive activity and toxicology of constituents from Bombax ceiba stem bark.

نویسندگان

  • Rubeena Saleem
  • Syed Iqbal Ahmad
  • Mohammad Ahmed
  • Zareen Faizi
  • Sadia Zikr-ur-Rehman
  • Muhammad Ali
  • Shaheen Faizi
چکیده

A novel constituent, shamimicin, 1"', 1"""'-bis-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,7-dihydroxy-5-O-xylopyranosyloxy-2H-1-benzopyran along with lupeol, which possesses potent hypotensive activity, has been isolated from Bombax ceiba stem bark. BCBMM--one of the most active hypotensive fractions has revealed its adverse effects on heart, liver and kidneys of mice at the dose of 1000 mg/kg/d.

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عنوان ژورنال:
  • Biological & pharmaceutical bulletin

دوره 26 1  شماره 

صفحات  -

تاریخ انتشار 2003